'CAT' RELATED POINTS IN MEDICINE

'CAT' RELATED POINTS IN MEDICINE


*Cat eye syndrome-partial Trisomy (22pter-22q11) Ref-Nelson

*Cat allergy-Fel d 1 is the major cat allergen,which can cause allergic manifestation in humans.Ref-Nelson

*Cat bite-Most common organism isolated "Pasteurella multocida''. Ref-Harrison

*Cat reflex-It is the other name of symmetric neck reflex.

*Cat cry syndrome- Cri-du-chat syndrome ,occurs due to deletion of 5p chromosome Ref-Nelson

*Cat scratch disease- It manifests by painful regional lymphadenopathy persisting for several weeks or months after a cat scratch.causative organism is Bartonella henselae.

*Cat flea typhus-Caused by Rickettsia felis,vector is etenocephalides felis,incubation period 8-16 days and duration of illness 8-16 days Ref -Harrison

List of Monoclonal Antobodies

List of Monoclonal Antobodies

• Abciximab ReoPro 1994 chimeric inhibition of glycoprotein IIb/IIIa Cardiovascular disease

• Infliximab chimeric I inhibition of TNF-a Inflammatory diseases

.Adalimumab human inhibition of TNF-a signalling Inflammatory diseases



• Natalizumab humanized T cell VLA4 receptor Inflammatory diseases . (esp autoimmune-related multiple sclerosis therapy)

• Omalizumab humanized Ig E Inflammatory diseases . (mainly allergy-related asthma therapy)

• Eculizumab humanized complement C5 Inflammatory diseases . (PNH)

• Efalizumab humanized CD11a Inflammatory diseases . (psoriasis)

• Alemtuzumab humanized CD52 CLL

Gemtuzumab humanized CD33 AML . (with calicheamicin)

• Ri - tuximab Rituxan, chimeric CD20 NHL

Ibritumomab tiuxetan murine CD20 NHL (with yttrium-90 or indium-111)

Tostumomab murine CD20 NHL

.Daclizumab humanized IL-2 receptor Transplant rejection

Basiliximab chimeric IL-2 receptor Transplant rejection

Muromonab murine CD3 Receptor Transplant rejection

• Bevaciz umab humanized vascular endothelial growth factor Colorectal cancer

Panitumumab human epidermal growth factor receptor Colorectal cancer

Cetuximab chimeric epidermal growth factor receptor Colorectal cancer

• Ranibizumab humanized vascular endothelial growth factor Macular degeneration

• Palivizumab humanized epitope of F protein of RSV Viral infection (espRSV)

• Trastuzumab humanized ErbB2 Breast cancer
-mab suffix monoclonal antibody.

if immediately before mab----u--its humane derived
. ---mo--its murine
. ----i----its chimeric.

Types of Tongues in Various Medical Conditions

Types of Tongues in Various Medical Conditions



HUNTERS TONGUE/MOELLERS TONGUE------ PERNICIOUS ANAEMIA

BALD TONGUEOF SANDWITH-----------NIACIN DEFICIENCY(PELLAGRA)

MAGENTA OR BEEFY RED TONGUE-----------RIBOFLAVIN DEFICIENCY

STRAW BERRY(EARLY)AND RASBERRY(LATE)------SCARLET FEVER

SCROTAL TONGUE-----FISSURE TONGUE

BLACK HAIRY TONGUE------PROLONGED ORAL USE OF ANTIBIOTICS.

CEREBRIFORM TONGUE-----A FEATURE OF PEMPHIGUS VEGETANS.

Vernet's syndrome

Jugular Foramen or Vernet's syndrome is characterized by the paresis of 9th–11th (with or without 12th) cranial nerves together.

Symptoms
Symptoms of this syndrome are consequences of this paresis. As such, in an affected patient, you may find:

dysphonia/hoarseness
soft palate dropping
deviation of the uvula towards the normal side
dysphagia
loss of sensory function from the posterior 1/3 of the tongue
decrease in the parotid gland secretion
loss of gag reflex
sternocleidomastoid and trapezius muscles paresis

Causes
Glomus tumors (most frequently)
Meningiomas
Schwannomas (Acoustic neuroma)
Metastatic tumors located at the cerebellopontine angle
Trauma
Infections
Cholesteatoma (very rare)