List of Monoclonal Antobodies

List of Monoclonal Antobodies

• Abciximab ReoPro 1994 chimeric inhibition of glycoprotein IIb/IIIa Cardiovascular disease

• Infliximab chimeric I inhibition of TNF-a Inflammatory diseases

.Adalimumab human inhibition of TNF-a signalling Inflammatory diseases



• Natalizumab humanized T cell VLA4 receptor Inflammatory diseases . (esp autoimmune-related multiple sclerosis therapy)

• Omalizumab humanized Ig E Inflammatory diseases . (mainly allergy-related asthma therapy)

• Eculizumab humanized complement C5 Inflammatory diseases . (PNH)

• Efalizumab humanized CD11a Inflammatory diseases . (psoriasis)

• Alemtuzumab humanized CD52 CLL

Gemtuzumab humanized CD33 AML . (with calicheamicin)

• Ri - tuximab Rituxan, chimeric CD20 NHL

Ibritumomab tiuxetan murine CD20 NHL (with yttrium-90 or indium-111)

Tostumomab murine CD20 NHL

.Daclizumab humanized IL-2 receptor Transplant rejection

Basiliximab chimeric IL-2 receptor Transplant rejection

Muromonab murine CD3 Receptor Transplant rejection

• Bevaciz umab humanized vascular endothelial growth factor Colorectal cancer

Panitumumab human epidermal growth factor receptor Colorectal cancer

Cetuximab chimeric epidermal growth factor receptor Colorectal cancer

• Ranibizumab humanized vascular endothelial growth factor Macular degeneration

• Palivizumab humanized epitope of F protein of RSV Viral infection (espRSV)

• Trastuzumab humanized ErbB2 Breast cancer
-mab suffix monoclonal antibody.

if immediately before mab----u--its humane derived
. ---mo--its murine
. ----i----its chimeric.